Hip fractures: Enhanced recovery and reduction in mortality with local anaesthetics

Using local anaesthetic infiltration has already been shown to reduce pain, morbidity and mortality after elective knee replacement operations. A new study from the UK, presented at the EFORT Congress in Istanbul, shows that this kind of enhanced recovery protocol has many benefits in postoperative care of patients undergoing hip operations.

Istanbul, 8  June 2013  – Patients undergoing hip operations have many benefits from an “enhanced recovery protocol” with local anaesthetic infiltrations, a new study shows. These include a reduced level of pain medication and reduced mortality. Patients treated under the protocol also had shorter stays in acute care and were less likely to need referral to rehabilitation  facilities.  The  study  undertaken  by  a  team  at  the  Northumbria  Healthcare Trust  (Newcastle-upon-Tyne,  UK)  sought  to  establish  whether  methods  known  to  reduce pain and improve survival rates after knee operations were also applicable after surgery for hip fractures. The team, Doctors W. Harrison, D. Lees, T. Ankers, J. A’Court, and M. R. Reed presenting their results at the 14th Congress of the European Federation of National Associations  of  Orthopaedics  and  Traumatology  (EFORT)  in  Istanbul,  show  that  these methods, involving direct delivery of pain relief via catheter to the wound and joint, and referred   to   as   an   enhanced   recovery   protocol   (ER),   can   be   of   significant   benefit   in postoperative care of hip surgeries. “The results of this study were striking,” said Dr William Harrison.  “We  feel  this  deserves  further  study.  We  are  continuing  to  use  ER  with  our patients, but multi-centre randomised trials should be completed before it can be recommended as standard practice in all centres.”

Drastic reduction in pain  relief requirements and  mortality

Patients undergoing surgery for hip fracture are dealing not only with pain from the initial trauma,   but   also   postoperative   pain.   Many   of   these   patients   are   elderly   and   pain medications carry significant risks of toxicity. For the study, which took place over a period of two years, data was analysed from around 400 patients, with a mean age of 80 years. Around 20% of those included served as a control group, while the rest received the ER protocol,  i.e.  controlled  infiltration  and  infusion  of  local  anaesthetics,  to  varying  degrees during postoperative care.

One of the most striking aspects of the Northumbria Healthcare Trust team’s results is the reduction in mortality during the acute hospital stay. “The ER protocol, by delivering pain relief  directly  to  the  wound  and  joint,  allowed  an  approximately  40%  reduction  in  opiate use.  However  Dr  Harrison  cautions  that  other  factors  may  have  played  a  role  in  the reduction in mortality. “The reduction may have been directly related to the ER protocol, but other  improvements  were  made  during  that  period  such  as  a  targeted  fourth  meal  every day for patients with hip fracture.”

The study also showed a marked decrease in the number of days patients recovering from hip fracture surgery spent on the orthopaedic ward, with a drop in mean stay from 12 days for those patients receiving traditional postoperative care to a mean 9.3 days for those receiving the enhanced recovery protocol. Furthermore, the ER protocol appears to have significant benefits in reducing pressure on rehabilitation facilities with approximately three times as many patients in the ER group discharged home directly from the acute ward.

Significant cost  benefits

Aside  from  the  incalculable  benefit  of  possibly  reducing  mortality  among  patients undergoing surgery for hip fracture, the enhanced recovery protocol may deliver significant savings for health systems. “In terms of injections, catheters and infusion pumps we spend an  additional  £62  per  patient,”  said  Dr  Harrison.  “We  haven’t  quantified  the  benefits  to patients but in our study each patient had a reduced acute stay of 2.7 days. Our unit costs a  day  in  hospital  at  around  £400  per  day.  Rehab  stay  was  also  shorter  and  potentially brings a further saving.” The study also concluded that there were no significant adverse events with the controlled infiltration and infusion of local anaesthetic.

About EFORT

The   European   Federation   of   National   Associations   of   Orthopaedics   and   Traumatology (EFORT) is the umbrella organisation linking Europe´s national orthopaedic societies. EFORT was founded in  1991 in  the Italian Marentino. Today it  has 42 national member societies from 43 member countries and six associate scientific members.

EFORT   is   a   non-profit   organisation.   The   participating   societies   aim   at   promoting   the exchange  of  scientific  knowledge  and  experience  in  the  prevention  and  treatment  of diseases and injuries of the musculoskeletal system. EFORT organises European congresses, seminars, courses, forums and conferences. It also initiates and supports basic and clinical research.

Source: EFORT Abstract 3732: Postoperative local anaesthetic infiltration and infusion by indwelling catheter for patients with a hip fracture: an enhanced recovery initiative.

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